Research Associate, Biology

At Kestrel our aspiration is to invent brilliant technologies and develop novel small molecule agents for cancer targets of exceptional scientific and clinical import, beginning with mutant RAS. Our reliance is on the rigorous application of innovative science in the service of the discovery of new medicines for people with cancer. Our priority is patients, always.

Kestrel is an oncology biotech start-up in its early stages of growth, having been in operation since January of 2022. We have excellent funding and, having moved into our new laboratory space in early 2023, are in the process of expanding our team.

We are seeking an outstanding individual to play an instrumental role in our in vitro biology research activities. The successful candidate will support the design and execution of biology studies to screen small molecules, demonstrate target engagement and biomarker modulation, and elucidate mechanism of action for Kestrel’s oncology drug candidates.

The successful candidate will assume the role of Research Associate, Biology and will report to the Principal Scientist, Biology.

Key Responsibilities

  • Perform routine cell culture and manage cell banking.
  • Optimize and perform biochemical and cellular assays (e.g., HTRF, ELISA, CTG, Western blotting) to support compound screening from hit-to-lead / lead optimization through to drug candidate nomination for discovery programs.
  • Support the characterization and mechanism of action studies for lead compounds.
  • Accurately record detailed documentation of experimental results via ELN (Electronic Lab Notebook)

Professional Experience & Qualifications

  • A or M.S. in cell / molecular biology, immunology, or related discipline.
  • 3+ years in the biotech / pharmaceutical industry or equivalent experience.
  • Strong scientific knowledge and research experience in cellular biology is required. Experience in cancer signaling pathways research and/or preclinical small molecule drug development is a plus.
  • Hands-on experience with a wide range of in-vitro cellular assays including cell culture, 2- and 3-D cell viability assays, cell line engineering (CRISPR, shRNA, overexpression), western blotting, immunoprecipitation, qPCR, reporter assays, and high throughput assay development (384-well). Experience in flow cytometry is a plus, but not necessary.
  • Demonstrated independence in experimental design, execution, data analysis and troubling shooting is required.
  • Attention to detail with excellent organizational and record-keeping skills is a requirement.
  • Excellent interpersonal skills with the ability to interact effectively and communicate clearly with team members is a requirement.
  • Proficiency in utilizing software such as Graph Pad, Microsoft office etc.

Kestrel Therapeutics offers a generous benefits package including medical, dental, vision, and disability insurance, as well as paid time off and a 401k plan.

Kestrel Therapeutics is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, ethnicity, color, national origin, religion, age, marital status, veteran status, disability, genetic information, sexual orientation, gender identity or any other basis protected by federal, state, or local law.

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